Why not? Less is more and if well achieved the task, you will end up with an amazing result. To do this you will need a good quality OPT and the valve which can do this task. It will need high mu where possible and linear. There are just a handful of DHT that could do the job (like EML20/30) or you can look for the high gm pentodes (e.g. E55L, E810F, etc.) which are very expensive generally or Russian valves like my beloved 6e5p which is cheap as chips (still).
Depending on the step down ratio of your OPT you will need likely a step up input transformer to drive the 6e5p to full tilt. Here is what I experimented with many years ago. Unfortunately I didn’t take any distortion measurements but it sounded really nice.
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